1916: Week 2
Nine games. Winners are listed first; numbers before names are AP ranks going in.
All games
| Sep 23, 1916 | Bucknell 31, Bloomsburg 0 | Box score |
| Sep 23, 1916 | California 23, Originals A.C. 0 | Box score |
| Sep 23, 1916 | Dartmouth 33, New Hampshire 0 | Box score |
| Sep 23, 1916 | Harvard 10, Colby 0 | Box score |
| Sep 23, 1916 | Oklahoma 27, Central Oklahoma 0 | Box score |
| Sep 23, 1916 | Oregon State Alumni 13, Oregon State 7upset | Box score |
| Sep 23, 1916 | Penn State 27, Susquehanna 0 | Box score |
| Sep 23, 1916 | Washington & Jefferson 37, Bethany (WV) 6 | Box score |
| Sep 23, 1916 | West Virginia Wesleyan 28, Davis & Elkins 0 | Box score |