1881: Week 6
Five games. Winners are listed first; numbers before names are AP ranks going in.
FBS vs. FBS
| Nov 8, 1881 | Rutgers 0, Columbia 0 | Box score |
| Nov 10, 1881 | Princeton 1, Rutgers 0 | Box score |
| Nov 12, 1881 | Princeton 1, Columbia 0 | Box score |
| Nov 12, 1881 | Yale 1, Harvard 0 | Box score |
Everyone else
| Nov 12, 1881 | Dartmouth 1, Amherst 0 | Box score |