| Oct 18, 1997 | Arizona State 31, 25Stanford 14upset | Box score |
| Oct 18, 1997 | Army 37, Rutgers 35 | Box score |
| Oct 18, 1997 | Ball State 37, Central Michigan 34 | Box score |
| Oct 18, 1997 | Boise State 17, North Texas 14upset | Box score |
| Oct 18, 1997 | BYU 17, Hawai’i 3 | Box score |
| Oct 18, 1997 | Colorado 42, Kansas 6 | Box score |
| Oct 18, 1997 | Colorado State 14, Wyoming 7 | Box score |
| Oct 18, 1997 | Eastern Michigan 45, Akron 0 | Box score |
| Oct 18, 1997 | 7Florida 24, 6Auburn 10upset | Box score |
| Oct 18, 1997 | 3Florida State 38, 21Georgia Tech 0 | Box score |
| Oct 18, 1997 | Fresno State 20, 18Air Force 17upset | Box score |
| Oct 18, 1997 | 19Georgia 34, Vanderbilt 13 | Box score |
| Oct 18, 1997 | Houston 41, Cincinnati 38 | Box score |
| Oct 18, 1997 | 20Kansas State 36, 14Texas A&M 17upset | Box score |
| Oct 18, 1997 | Kentucky 49, UL Monroe 14 | Box score |
| Oct 18, 1997 | Louisiana Tech 42, Arkansas State 14 | Box score |
| Oct 18, 1997 | Miami 45, Boston College 44 | Box score |
| Oct 18, 1997 | Miami (OH) 45, Marshall 21 | Box score |
| Oct 18, 1997 | 5Michigan 28, 15Iowa 24 | Box score |
| Oct 18, 1997 | Ole Miss 36, 8LSU 21upset | Box score |
| Oct 18, 1997 | Missouri 37, Texas 29 | Box score |
| Oct 18, 1997 | 2Nebraska 29, Texas Tech 0 | Box score |
| Oct 18, 1997 | Nevada 42, Idaho 23 | Box score |
| Oct 18, 1997 | 4North Carolina 20, NC State 7 | Box score |
| Oct 18, 1997 | Northwestern 19, 12Michigan State 17upset | Box score |
| Oct 18, 1997 | Ohio 24, Bowling Green 0 | Box score |
| Oct 18, 1997 | 11Ohio State 31, Indiana 0 | Box score |
| Oct 18, 1997 | Oklahoma 24, Baylor 23 | Box score |
| Oct 18, 1997 | Oregon 31, Utah 13 | Box score |
| Oct 18, 1997 | 1Penn State 16, Minnesota 15 | Box score |
| Oct 18, 1997 | Purdue 45, 24Wisconsin 20upset | Box score |
| Oct 18, 1997 | Rice 35, New Mexico 23 | Box score |
| Oct 18, 1997 | San Diego State 20, UNLV 17 | Box score |
| Oct 18, 1997 | San José State 10, UTEP 7 | Box score |
| Oct 18, 1997 | South Carolina 39, Arkansas 13 | Box score |
| Oct 18, 1997 | USC 20, Notre Dame 17 | Box score |
| Oct 18, 1997 | Syracuse 60, Temple 7 | Box score |
| Oct 18, 1997 | 9Tennessee 38, Alabama 21 | Box score |
| Oct 18, 1997 | Toledo 41, Northern Illinois 14 | Box score |
| Oct 18, 1997 | Tulane 33, East Carolina 16 | Box score |
| Oct 18, 1997 | Tulsa 33, TCU 22 | Box score |
| Oct 18, 1997 | 17UCLA 34, Oregon State 10 | Box score |
| Oct 18, 1997 | Utah State 38, New Mexico State 7 | Box score |
| Oct 18, 1997 | Virginia 13, Duke 10 | Box score |
| Oct 18, 1997 | Wake Forest 35, Maryland 17 | Box score |
| Oct 18, 1997 | 10Washington 58, Arizona 28 | Box score |
| Oct 18, 1997 | 13Washington State 63, California 37 | Box score |
| Oct 18, 1997 | Western Michigan 50, Kent State 27 | Box score |