| Sep 21, 1995 | North Carolina 17, Louisville 10 | Box score |
| Sep 23, 1995 | Arizona State 20, Oregon State 11 | Box score |
| Sep 23, 1995 | Arkansas 27, Memphis 20 | Box score |
| Sep 23, 1995 | Ball State 10, Western Michigan 0 | Box score |
| Sep 23, 1995 | Baylor 14, NC State 0 | Box score |
| Sep 23, 1995 | California 40, San José State 7 | Box score |
| Sep 23, 1995 | Central Michigan 22, Bowling Green 16 | Box score |
| Sep 23, 1995 | 7Colorado 29, 3Texas A&M 21upset | Box score |
| Sep 23, 1995 | Eastern Michigan 31, Ohio 20 | Box score |
| Sep 23, 1995 | Hawai’i 42, UTEP 21 | Box score |
| Sep 23, 1995 | Illinois 7, East Carolina 0 | Box score |
| Sep 23, 1995 | Indiana 27, Southern Miss 26 | Box score |
| Sep 23, 1995 | Iowa State 57, UNLV 30 | Box score |
| Sep 23, 1995 | Kansas 20, Houston 13 | Box score |
| Sep 23, 1995 | 19Kansas State 67, Akron 0 | Box score |
| Sep 23, 1995 | Kentucky 35, South Carolina 30upset | Box score |
| Sep 23, 1995 | 18LSU 52, Rice 7 | Box score |
| Sep 23, 1995 | Louisiana Tech 28, Arkansas State 25 | Box score |
| Sep 23, 1995 | 24Maryland 41, Duke 28 | Box score |
| Sep 23, 1995 | Miami (OH) 23, Cincinnati 16 | Box score |
| Sep 23, 1995 | Purdue 35, Michigan State 35 | Box score |
| Sep 23, 1995 | Ole Miss 18, 20Georgia 10upset | Box score |
| Sep 23, 1995 | Missouri 31, UL Monroe 22 | Box score |
| Sep 23, 1995 | 2Nebraska 49, Pacific 7 | Box score |
| Sep 23, 1995 | New Mexico 36, New Mexico State 24 | Box score |
| Sep 23, 1995 | Northern Illinois 25, Louisiana 24 | Box score |
| Sep 23, 1995 | Northwestern 30, Air Force 6 | Box score |
| Sep 23, 1995 | 21Notre Dame 55, 13Texas 27upset | Box score |
| Sep 23, 1995 | 8Ohio State 54, Pittsburgh 14 | Box score |
| Sep 23, 1995 | 10Oklahoma 51, North Texas 10 | Box score |
| Sep 23, 1995 | 6Penn State 59, Rutgers 34 | Box score |
| Sep 23, 1995 | 5USC 31, 25Arizona 10 | Box score |
| Sep 23, 1995 | Stanford 28, 12Oregon 21upset | Box score |
| Sep 23, 1995 | Syracuse 27, Minnesota 17 | Box score |
| Sep 23, 1995 | 15Tennessee 52, Mississippi State 14 | Box score |
| Sep 23, 1995 | TCU 16, Vanderbilt 3 | Box score |
| Sep 23, 1995 | Toledo 49, Nevada 35upset | Box score |
| Sep 23, 1995 | Utah 25, Fresno State 21 | Box score |
| Sep 23, 1995 | 11Virginia 22, Clemson 3 | Box score |
| Sep 23, 1995 | Virginia Tech 13, 17Miami 7upset | Box score |
| Sep 23, 1995 | Wake Forest 30, Navy 7upset | Box score |
| Sep 23, 1995 | 22Washington 21, Army 13 | Box score |
| Sep 23, 1995 | Washington State 24, 16UCLA 15upset | Box score |
| Sep 23, 1995 | West Virginia 45, Kent State 6 | Box score |
| Sep 23, 1995 | Wisconsin 42, SMU 0 | Box score |
| Sep 23, 1995 | Wyoming 45, Oklahoma State 25 | Box score |