| Oct 15, 1992 | Southern Miss 17, Tulane 7 | Box score |
| Oct 17, 1992 | Akron 22, Ball State 14 | Box score |
| Oct 17, 1992 | 4Alabama 17, 13Tennessee 10 | Box score |
| Oct 17, 1992 | Arizona 21, 8Stanford 6upset | Box score |
| Oct 17, 1992 | Arizona State 40, Oregon State 13 | Box score |
| Oct 17, 1992 | Baylor 29, Houston 23 | Box score |
| Oct 17, 1992 | 20Boston College 35, 9Penn State 32upset | Box score |
| Oct 17, 1992 | Bowling Green 10, Toledo 9 | Box score |
| Oct 17, 1992 | BYU 31, Wyoming 28 | Box score |
| Oct 17, 1992 | Cal State Fullerton 14, Louisiana 10upset | Box score |
| Oct 17, 1992 | Central Michigan 35, Kent State 0 | Box score |
| Oct 17, 1992 | 19Clemson 21, Duke 6 | Box score |
| Oct 17, 1992 | Colorado State 32, Air Force 28upset | Box score |
| Oct 17, 1992 | East Carolina 42, Cincinnati 21 | Box score |
| Oct 17, 1992 | 23Florida 24, Auburn 9 | Box score |
| Oct 17, 1992 | 6Florida State 29, 16Georgia Tech 24 | Box score |
| Oct 17, 1992 | 10Georgia 30, Vanderbilt 20 | Box score |
| Oct 17, 1992 | Hawai’i 47, Fresno State 45 | Box score |
| Oct 17, 1992 | Iowa 24, Illinois 14 | Box score |
| Oct 17, 1992 | 25Kansas 50, Iowa State 47 | Box score |
| Oct 17, 1992 | Kentucky 27, LSU 25 | Box score |
| Oct 17, 1992 | Louisville 32, Tulsa 27 | Box score |
| Oct 17, 1992 | Memphis 37, Arkansas State 7 | Box score |
| Oct 17, 1992 | 2Miami 45, TCU 10 | Box score |
| Oct 17, 1992 | Miami (OH) 23, Ohio 21 | Box score |
| Oct 17, 1992 | 3Michigan 31, Indiana 3 | Box score |
| Oct 17, 1992 | Michigan State 20, Minnesota 15 | Box score |
| Oct 17, 1992 | Ole Miss 17, Arkansas 3 | Box score |
| Oct 17, 1992 | Nevada 14, UNLV 10 | Box score |
| Oct 17, 1992 | New Mexico 24, Utah 7upset | Box score |
| Oct 17, 1992 | North Carolina 27, 17Virginia 7upset | Box score |
| Oct 17, 1992 | Virginia Tech 13, 21NC State 13 | Box score |
| Oct 17, 1992 | Ohio State 31, Northwestern 7 | Box score |
| Oct 17, 1992 | 7Colorado 24, Oklahoma 24 | Box score |
| Oct 17, 1992 | Oklahoma State 28, Missouri 26 | Box score |
| Oct 17, 1992 | Pacific 49, New Mexico State 17 | Box score |
| Oct 17, 1992 | Pittsburgh 27, Temple 20 | Box score |
| Oct 17, 1992 | Rutgers 45, Army 10 | Box score |
| Oct 17, 1992 | San Diego State 49, UTEP 27 | Box score |
| Oct 17, 1992 | South Carolina 21, 15Mississippi State 6upset | Box score |
| Oct 17, 1992 | 18USC 27, California 24 | Box score |
| Oct 17, 1992 | 14Syracuse 20, 24West Virginia 17 | Box score |
| Oct 17, 1992 | 5Texas A&M 35, Rice 9 | Box score |
| Oct 17, 1992 | Utah State 28, Kansas State 16 | Box score |
| Oct 17, 1992 | Wake Forest 30, Maryland 23 | Box score |
| Oct 17, 1992 | 1Washington 24, Oregon 3 | Box score |
| Oct 17, 1992 | 22Washington State 30, UCLA 17 | Box score |
| Oct 17, 1992 | Western Michigan 20, Eastern Michigan 19 | Box score |
| Oct 17, 1992 | Wisconsin 19, Purdue 16 | Box score |