| Sep 23, 1989 | Air Force 43, UTEP 26 | Box score |
| Sep 23, 1989 | 15Alabama 15, Kentucky 3 | Box score |
| Sep 23, 1989 | 23Arizona 20, 11Washington 17upset | Box score |
| Sep 23, 1989 | 8Arkansas 24, Ole Miss 17 | Box score |
| Sep 23, 1989 | Army 14, Wake Forest 10 | Box score |
| Sep 23, 1989 | Baylor 46, Kansas 3 | Box score |
| Sep 23, 1989 | Bowling Green 24, Central Michigan 20 | Box score |
| Sep 23, 1989 | San Diego State 41, Cal State Fullerton 41 | Box score |
| Sep 23, 1989 | California 20, Wisconsin 14 | Box score |
| Sep 23, 1989 | Cincinnati 30, Miami (OH) 14 | Box score |
| Sep 23, 1989 | 7Clemson 31, Maryland 7 | Box score |
| Sep 23, 1989 | Colorado State 35, Eastern Michigan 35 | Box score |
| Sep 23, 1989 | Florida 38, Memphis 13 | Box score |
| Sep 23, 1989 | Florida State 59, Tulane 9 | Box score |
| Sep 23, 1989 | Fresno State 52, Long Beach State 0 | Box score |
| Sep 23, 1989 | Georgia 23, Mississippi State 6 | Box score |
| Sep 23, 1989 | Hawai’i 67, Utah 20 | Box score |
| Sep 23, 1989 | 17Houston 36, Arizona State 7 | Box score |
| Sep 23, 1989 | 20Illinois 41, Utah State 2 | Box score |
| Sep 23, 1989 | Iowa 31, Iowa State 21 | Box score |
| Sep 23, 1989 | Louisiana 18, Rice 3 | Box score |
| Sep 23, 1989 | 2Miami 38, Missouri 7 | Box score |
| Sep 23, 1989 | 5Michigan 24, 24UCLA 23 | Box score |
| Sep 23, 1989 | 3Nebraska 48, Minnesota 0 | Box score |
| Sep 23, 1989 | UNLV 26, New Mexico State 14 | Box score |
| Sep 23, 1989 | 18NC State 40, North Carolina 6 | Box score |
| Sep 23, 1989 | Northern Illinois 37, Kansas State 20 | Box score |
| Sep 23, 1989 | 1Notre Dame 21, Michigan State 13 | Box score |
| Sep 23, 1989 | Penn State 7, Boston College 3 | Box score |
| Sep 23, 1989 | 13Pittsburgh 30, 10Syracuse 23upset | Box score |
| Sep 23, 1989 | Rutgers 38, Northwestern 27 | Box score |
| Sep 23, 1989 | San José State 41, Pacific 32 | Box score |
| Sep 23, 1989 | South Carolina 21, Georgia Tech 10 | Box score |
| Sep 23, 1989 | 12USC 42, 25Ohio State 3 | Box score |
| Sep 23, 1989 | Stanford 18, 22Oregon 17upset | Box score |
| Sep 23, 1989 | Texas 45, SMU 13 | Box score |
| Sep 23, 1989 | TCU 19, Southern Miss 17 | Box score |
| Sep 23, 1989 | Texas Tech 31, Oklahoma State 15 | Box score |
| Sep 23, 1989 | Toledo 29, Ball State 22 | Box score |
| Sep 23, 1989 | Tulsa 35, New Mexico 33 | Box score |
| Sep 23, 1989 | Vanderbilt 54, Ohio 10 | Box score |
| Sep 23, 1989 | Virginia 49, Duke 28 | Box score |
| Sep 23, 1989 | Virginia Tech 23, Temple 0 | Box score |
| Sep 23, 1989 | 19Washington State 29, Wyoming 23 | Box score |
| Sep 23, 1989 | 9West Virginia 30, Louisville 21 | Box score |
| Sep 23, 1989 | Western Michigan 26, Kent State 4 | Box score |