1980: Week 15
Two games. One ranked team lost. One game matched two ranked teams. Winners are listed first; numbers before names are AP ranks going in.
The week in review
Ranked against ranked
| Dec 6, 1980 | 17USC 20, 2Notre Dame 3upset | Box score |
Upsets
| Dec 6, 1980 | 17USC 20, 2Notre Dame 3upset | Box score |
A ranked team beaten as the betting favorite, or, where no line is on file, by an unranked or lower-ranked team.
FBS vs. FBS
| Dec 6, 1980 | 3Florida State 17, Florida 13 | Box score |
| Dec 6, 1980 | 17USC 20, 2Notre Dame 3upset | Box score |