| Sep 18, 1976 | 14Alabama 56, SMU 3 | Box score |
| Sep 18, 1976 | App State 31, VMI 12 | Box score |
| Sep 18, 1976 | 12Arkansas 16, Oklahoma State 10 | Box score |
| Sep 18, 1976 | Army 26, Holy Cross 24 | Box score |
| Sep 18, 1976 | Ball State 23, Miami (OH) 6upset | Box score |
| Sep 18, 1976 | Baylor 15, Auburn 14upset | Box score |
| Sep 18, 1976 | Bowling Green 53, Eastern Michigan 12 | Box score |
| Sep 18, 1976 | BYU 42, Colorado State 18 | Box score |
| Sep 18, 1976 | Brown 14, Yale 6 | Box score |
| Sep 18, 1976 | Central Michigan 9, Toledo 7 | Box score |
| Sep 18, 1976 | Colgate 17, Davidson 7 | Box score |
| Sep 18, 1976 | Colorado 21, Washington 7 | Box score |
| Sep 18, 1976 | Dartmouth 20, Pennsylvania 0 | Box score |
| Sep 18, 1976 | East Carolina 23, NC State 14 | Box score |
| Sep 18, 1976 | Florida 49, Houston 14 | Box score |
| Sep 18, 1976 | 9Georgia 41, Clemson 0 | Box score |
| Sep 18, 1976 | Harvard 34, Columbia 10 | Box score |
| Sep 18, 1976 | Idaho 31, Pacific 28 | Box score |
| Sep 18, 1976 | Illinois 31, 6Missouri 6upset | Box score |
| Sep 18, 1976 | Indiana State 31, Arkansas State 21upset | Box score |
| Sep 18, 1976 | Iowa 41, Syracuse 3 | Box score |
| Sep 18, 1976 | Iowa State 41, Air Force 6 | Box score |
| Sep 18, 1976 | 13Kansas 37, Kentucky 16 | Box score |
| Sep 18, 1976 | Long Beach State 32, Utah State 10 | Box score |
| Sep 18, 1976 | Louisiana 7, Cincinnati 3 | Box score |
| Sep 18, 1976 | 16LSU 28, Oregon State 11 | Box score |
| Sep 18, 1976 | UL Monroe 16, Lamar 6 | Box score |
| Sep 18, 1976 | Marshall 23, Illinois State 13 | Box score |
| Sep 18, 1976 | 10Maryland 24, West Virginia 3 | Box score |
| Sep 18, 1976 | McNeese 15, Louisiana Tech 13upset | Box score |
| Sep 18, 1976 | Miami 47, Florida State 0 | Box score |
| Sep 18, 1976 | 1Michigan 51, Stanford 0 | Box score |
| Sep 18, 1976 | Michigan State 21, Wyoming 10 | Box score |
| Sep 18, 1976 | Minnesota 28, Washington State 14 | Box score |
| Sep 18, 1976 | 20Ole Miss 34, Tulane 7 | Box score |
| Sep 18, 1976 | Mississippi State 30, Louisville 21 | Box score |
| Sep 18, 1976 | 8Nebraska 45, Indiana 13 | Box score |
| Sep 18, 1976 | New Mexico 25, UTEP 7 | Box score |
| Sep 18, 1976 | 17North Carolina 12, Northwestern 0 | Box score |
| Sep 18, 1976 | Notre Dame 23, Purdue 0 | Box score |
| Sep 18, 1976 | Ohio 14, Kent State 12 | Box score |
| Sep 18, 1976 | 2Ohio State 12, 7Penn State 7 | Box score |
| Sep 18, 1976 | 4Oklahoma 28, California 17 | Box score |
| Sep 18, 1976 | 3Pittsburgh 42, Georgia Tech 14 | Box score |
| Sep 18, 1976 | Princeton 3, Cornell 0 | Box score |
| Sep 18, 1976 | Rice 43, Utah 22 | Box score |
| Sep 18, 1976 | San Diego State 7, Fresno State 3 | Box score |
| Sep 18, 1976 | San José State 20, Cal State Fullerton 0 | Box score |
| Sep 18, 1976 | South Carolina 24, Duke 6 | Box score |
| Sep 18, 1976 | USC 53, Oregon 0 | Box score |
| Sep 18, 1976 | Southern Illinois 27, Drake 15upset | Box score |
| Sep 18, 1976 | Tennessee 31, TCU 0 | Box score |
| Sep 18, 1976 | 19Texas 17, North Texas 14 | Box score |
| Sep 18, 1976 | 11Texas A&M 34, Kansas State 14 | Box score |
| Sep 18, 1976 | Texas–Arlington 21, New Mexico State 10 | Box score |
| Sep 18, 1976 | Tulsa 16, Memphis 14 | Box score |
| Sep 18, 1976 | 5UCLA 37, Arizona 9 | Box score |
| Sep 18, 1976 | Vanderbilt 27, Wake Forest 24 | Box score |
| Sep 18, 1976 | Villanova 31, Dayton 30 | Box score |
| Sep 18, 1976 | Virginia Tech 16, Southern Miss 7 | Box score |
| Sep 18, 1976 | West Texas 14, Wichita State 12 | Box score |
| Sep 18, 1976 | Western Michigan 37, Northern Illinois 6 | Box score |
| Sep 18, 1976 | William & Mary 14, Virginia 0 | Box score |