| Oct 8, 1971 | San José State 30, Long Beach State 28upset | Box score |
| Oct 9, 1971 | Air Force 30, SMU 0 | Box score |
| Oct 9, 1971 | 6Alabama 42, Vanderbilt 0 | Box score |
| Oct 9, 1971 | 12Arizona State 42, Colorado State 0 | Box score |
| Oct 9, 1971 | 17Arkansas 35, Baylor 7 | Box score |
| Oct 9, 1971 | 4Auburn 27, Southern Miss 14 | Box score |
| Oct 9, 1971 | Boston College 23, Villanova 7 | Box score |
| Oct 9, 1971 | California 30, Oregon State 27 | Box score |
| Oct 9, 1971 | Cincinnati 30, Xavier 7 | Box score |
| Oct 9, 1971 | The Citadel 25, VMI 24 | Box score |
| Oct 9, 1971 | Clemson 3, 14Duke 0upset | Box score |
| Oct 9, 1971 | 5Colorado 24, Iowa State 14 | Box score |
| Oct 9, 1971 | Cornell 19, Princeton 8 | Box score |
| Oct 9, 1971 | Dartmouth 19, Pennsylvania 3 | Box score |
| Oct 9, 1971 | Florida State 27, Mississippi State 9 | Box score |
| Oct 9, 1971 | 10Georgia 38, Ole Miss 7 | Box score |
| Oct 9, 1971 | Harvard 21, Columbia 19 | Box score |
| Oct 9, 1971 | Hawai’i 26, Cal State Los Angeles 0 | Box score |
| Oct 9, 1971 | Holy Cross 28, Colgate 14 | Box score |
| Oct 9, 1971 | Kansas 39, Kansas State 13 | Box score |
| Oct 9, 1971 | 16LSU 48, Florida 7 | Box score |
| Oct 9, 1971 | Louisville 26, Memphis 20 | Box score |
| Oct 9, 1971 | 2Michigan 24, Michigan State 13 | Box score |
| Oct 9, 1971 | 1Nebraska 36, Missouri 0 | Box score |
| Oct 9, 1971 | New Mexico 35, New Mexico State 35 | Box score |
| Oct 9, 1971 | NC State 21, Wake Forest 14 | Box score |
| Oct 9, 1971 | Northern Illinois 37, Marshall 18 | Box score |
| Oct 9, 1971 | Northwestern 28, Iowa 3 | Box score |
| Oct 9, 1971 | 7Notre Dame 17, Miami 0 | Box score |
| Oct 9, 1971 | Ohio 35, Kentucky 6 | Box score |
| Oct 9, 1971 | 15Ohio State 24, Illinois 10 | Box score |
| Oct 9, 1971 | 8Oklahoma 48, 3Texas 27upset | Box score |
| Oct 9, 1971 | TCU 14, Oklahoma State 14 | Box score |
| Oct 9, 1971 | Oregon 28, USC 23upset | Box score |
| Oct 9, 1971 | 9Penn State 42, Army 0 | Box score |
| Oct 9, 1971 | Pittsburgh 36, Navy 35 | Box score |
| Oct 9, 1971 | Purdue 27, Minnesota 13 | Box score |
| Oct 9, 1971 | Richmond 14, East Carolina 7 | Box score |
| Oct 9, 1971 | San Diego State 14, Pacific 7 | Box score |
| Oct 9, 1971 | South Carolina 34, Virginia 14 | Box score |
| Oct 9, 1971 | 19Stanford 17, 11Washington 6upset | Box score |
| Oct 9, 1971 | Syracuse 21, Maryland 13 | Box score |
| Oct 9, 1971 | Tampa 47, Dayton 14 | Box score |
| Oct 9, 1971 | 13Tennessee 10, Georgia Tech 6 | Box score |
| Oct 9, 1971 | Texas Tech 28, Texas A&M 7 | Box score |
| Oct 9, 1971 | Texas–Arlington 13, West Texas 0upset | Box score |
| Oct 9, 1971 | 20Toledo 24, Bowling Green 7 | Box score |
| Oct 9, 1971 | Tulane 37, 18North Carolina 29upset | Box score |
| Oct 9, 1971 | Tulsa 46, Virginia Tech 39 | Box score |
| Oct 9, 1971 | UCLA 34, Washington State 21 | Box score |
| Oct 9, 1971 | Utah 32, UTEP 10 | Box score |
| Oct 9, 1971 | Utah State 29, BYU 7 | Box score |
| Oct 9, 1971 | West Virginia 28, William & Mary 23 | Box score |
| Oct 9, 1971 | Western Michigan 31, Kent State 0 | Box score |
| Oct 9, 1971 | Wisconsin 35, Indiana 29 | Box score |
| Oct 9, 1971 | Wyoming 14, Arizona 3 | Box score |
| Oct 9, 1971 | Yale 17, Brown 10 | Box score |