| Oct 30, 1964 | Miami 10, Detroit Mercy 7 | Box score |
| Oct 31, 1964 | Air Force 7, Arizona 0 | Box score |
| Oct 31, 1964 | 3Alabama 23, Mississippi State 6 | Box score |
| Oct 31, 1964 | Arizona State 34, Colorado State 6 | Box score |
| Oct 31, 1964 | 4Arkansas 17, Texas A&M 0 | Box score |
| Oct 31, 1964 | Army 9, Iowa State 7 | Box score |
| Oct 31, 1964 | Bowling Green 21, Miami (OH) 18 | Box score |
| Oct 31, 1964 | BYU 28, Utah State 14upset | Box score |
| Oct 31, 1964 | Clemson 29, Virginia 7 | Box score |
| Oct 31, 1964 | Cornell 57, Columbia 20 | Box score |
| Oct 31, 1964 | East Carolina 19, The Citadel 10 | Box score |
| Oct 31, 1964 | 10Florida 14, Auburn 0 | Box score |
| Oct 31, 1964 | Florida State 34, Southern Miss 0 | Box score |
| Oct 31, 1964 | George Washington 17, Cincinnati 15upset | Box score |
| Oct 31, 1964 | Georgia 24, North Carolina 8 | Box score |
| Oct 31, 1964 | 8Georgia Tech 21, Duke 8 | Box score |
| Oct 31, 1964 | Harvard 34, Pennsylvania 0 | Box score |
| Oct 31, 1964 | Holy Cross 36, Richmond 22 | Box score |
| Oct 31, 1964 | Idaho 40, Pacific 0 | Box score |
| Oct 31, 1964 | Kansas 7, Kansas State 0 | Box score |
| Oct 31, 1964 | Kent State 14, Toledo 11 | Box score |
| Oct 31, 1964 | 9LSU 11, Ole Miss 10 | Box score |
| Oct 31, 1964 | Marshall 16, Western Michigan 7 | Box score |
| Oct 31, 1964 | Memphis 23, Wake Forest 14 | Box score |
| Oct 31, 1964 | Michigan 35, Northwestern 0 | Box score |
| Oct 31, 1964 | Michigan State 22, Wisconsin 6 | Box score |
| Oct 31, 1964 | Minnesota 21, Indiana 0 | Box score |
| Oct 31, 1964 | 5Nebraska 9, Missouri 0 | Box score |
| Oct 31, 1964 | New Mexico 17, Wyoming 6 | Box score |
| Oct 31, 1964 | NC State 17, South Carolina 14 | Box score |
| Oct 31, 1964 | 2Notre Dame 40, Navy 0 | Box score |
| Oct 31, 1964 | Ohio 24, Dayton 0 | Box score |
| Oct 31, 1964 | 1Ohio State 21, Iowa 19 | Box score |
| Oct 31, 1964 | Oklahoma 14, Colorado 11 | Box score |
| Oct 31, 1964 | Oregon State 24, Washington State 7 | Box score |
| Oct 31, 1964 | Penn State 17, Maryland 9 | Box score |
| Oct 31, 1964 | Princeton 14, Brown 0 | Box score |
| Oct 31, 1964 | Purdue 26, Illinois 14 | Box score |
| Oct 31, 1964 | Rutgers 9, Boston University 0 | Box score |
| Oct 31, 1964 | Stanford 10, 7Oregon 8upset | Box score |
| Oct 31, 1964 | Syracuse 21, Pittsburgh 6 | Box score |
| Oct 31, 1964 | 6Texas 7, SMU 0 | Box score |
| Oct 31, 1964 | TCU 17, Baylor 14 | Box score |
| Oct 31, 1964 | Rice 6, Texas Tech 6 | Box score |
| Oct 31, 1964 | Tulane 25, VMI 6 | Box score |
| Oct 31, 1964 | Tulsa 61, Oklahoma State 14 | Box score |
| Oct 31, 1964 | UCLA 25, California 21 | Box score |
| Oct 31, 1964 | Utah 41, UTEP 0 | Box score |
| Oct 31, 1964 | Villanova 31, Xavier 13 | Box score |
| Oct 31, 1964 | Virginia Tech 27, William & Mary 20 | Box score |
| Oct 31, 1964 | Washington 14, USC 13upset | Box score |
| Oct 31, 1964 | West Texas 18, San José State 7 | Box score |
| Oct 31, 1964 | West Virginia 26, Kentucky 21 | Box score |
| Oct 31, 1964 | Wichita State 23, Louisville 15 | Box score |
| Oct 31, 1964 | Yale 24, Dartmouth 15 | Box score |