| Sep 24, 1964 | 7Washington 35, Baylor 14 | Box score |
| Sep 25, 1964 | Detroit Mercy 22, Toledo 6 | Box score |
| Sep 25, 1964 | Houston 10, Texas A&M 0 | Box score |
| Sep 26, 1964 | 6Alabama 36, Tulane 6 | Box score |
| Sep 26, 1964 | Arizona 39, BYU 6 | Box score |
| Sep 26, 1964 | Arizona State 34, West Texas 8 | Box score |
| Sep 26, 1964 | Arkansas 31, Tulsa 22 | Box score |
| Sep 26, 1964 | Army 19, Boston College 13 | Box score |
| Sep 26, 1964 | 8Auburn 3, Tennessee 0 | Box score |
| Sep 26, 1964 | Boston University 15, George Washington 7 | Box score |
| Sep 26, 1964 | Bowling Green 21, North Texas 7 | Box score |
| Sep 26, 1964 | Cornell 9, Buffalo 9 | Box score |
| Sep 26, 1964 | Cincinnati 20, Dayton 10 | Box score |
| Sep 26, 1964 | Colorado State 7, Pacific 0 | Box score |
| Sep 26, 1964 | Columbia 21, Colgate 14 | Box score |
| Sep 26, 1964 | Duke 30, Virginia 0 | Box score |
| Sep 26, 1964 | Florida 16, Mississippi State 13 | Box score |
| Sep 26, 1964 | Florida State 10, TCU 0 | Box score |
| Sep 26, 1964 | Georgia 7, Vanderbilt 0 | Box score |
| Sep 26, 1964 | Georgia Tech 20, Miami 0 | Box score |
| Sep 26, 1964 | 3Illinois 20, California 14 | Box score |
| Sep 26, 1964 | Iowa 34, Idaho 24 | Box score |
| Sep 26, 1964 | Kent State 15, Xavier 2 | Box score |
| Sep 26, 1964 | Kentucky 27, 1Ole Miss 21upset | Box score |
| Sep 26, 1964 | LSU 3, Rice 0 | Box score |
| Sep 26, 1964 | Maryland 24, South Carolina 6 | Box score |
| Sep 26, 1964 | Miami (OH) 21, Marshall 0 | Box score |
| Sep 26, 1964 | Michigan 24, Air Force 7 | Box score |
| Sep 26, 1964 | Missouri 23, Utah 6 | Box score |
| Sep 26, 1964 | 10Navy 35, William & Mary 6 | Box score |
| Sep 26, 1964 | Nebraska 26, Minnesota 21 | Box score |
| Sep 26, 1964 | North Carolina 21, Michigan State 15 | Box score |
| Sep 26, 1964 | NC State 9, Clemson 0 | Box score |
| Sep 26, 1964 | Northwestern 14, Indiana 13 | Box score |
| Sep 26, 1964 | Notre Dame 31, Wisconsin 7upset | Box score |
| Sep 26, 1964 | 5Ohio State 27, SMU 8 | Box score |
| Sep 26, 1964 | Oklahoma State 29, Iowa State 14 | Box score |
| Sep 26, 1964 | Oregon 22, Pittsburgh 13 | Box score |
| Sep 26, 1964 | Oregon State 14, Colorado 7 | Box score |
| Sep 26, 1964 | Princeton 10, Rutgers 7 | Box score |
| Sep 26, 1964 | Purdue 17, Ohio 0 | Box score |
| Sep 26, 1964 | Richmond 20, VMI 14 | Box score |
| Sep 26, 1964 | USC 40, 2Oklahoma 14upset | Box score |
| Sep 26, 1964 | Stanford 10, San José State 8 | Box score |
| Sep 26, 1964 | 9Syracuse 38, Kansas 6 | Box score |
| Sep 26, 1964 | 4Texas 23, Texas Tech 0 | Box score |
| Sep 26, 1964 | UCLA 21, Penn State 14 | Box score |
| Sep 26, 1964 | Utah State 76, New Mexico State 0 | Box score |
| Sep 26, 1964 | Villanova 32, Holy Cross 0 | Box score |
| Sep 26, 1964 | Wake Forest 38, Virginia Tech 21upset | Box score |
| Sep 26, 1964 | West Virginia 7, The Citadel 3 | Box score |
| Sep 26, 1964 | Wyoming 28, Washington State 7 | Box score |