1963: Week 2
50 games. One ranked team lost, to an unranked team. Winners are listed first; numbers before names are AP ranks going in.
The week in review
Upsets
A ranked team beaten as the betting favorite, or, where no line is on file, by an unranked or lower-ranked team.
FBS vs. FBS
| Sep 20, 1963 | Florida State 24, Miami 0 | Box score |
| Sep 20, 1963 | Pittsburgh 20, UCLA 0 | Box score |
| Sep 20, 1963 | 5Texas 21, Tulane 0 | Box score |
| Sep 21, 1963 | Air Force 10, 10Washington 7upset | Box score |
| Sep 21, 1963 | 3Alabama 32, Georgia 7 | Box score |
| Sep 21, 1963 | 8Arkansas 21, Oklahoma State 0 | Box score |
| Sep 21, 1963 | Army 30, Boston University 0 | Box score |
| Sep 21, 1963 | Auburn 21, Houston 14 | Box score |
| Sep 21, 1963 | Bowling Green 27, Detroit Mercy 14 | Box score |
| Sep 21, 1963 | Buffalo 7, Ohio 0upset | Box score |
| Sep 21, 1963 | California 15, Iowa State 8 | Box score |
| Sep 21, 1963 | Cincinnati 28, Drake 0 | Box score |
| Sep 21, 1963 | Colorado State 20, Pacific 0upset | Box score |
| Sep 21, 1963 | Dayton 22, Toledo 19 | Box score |
| Sep 21, 1963 | Duke 22, South Carolina 14 | Box score |
| Sep 21, 1963 | East Carolina 20, Wake Forest 10 | Box score |
| Sep 21, 1963 | Kansas State 24, BYU 7 | Box score |
| Sep 21, 1963 | Kentucky 33, Virginia Tech 14 | Box score |
| Sep 21, 1963 | LSU 14, Texas A&M 6 | Box score |
| Sep 21, 1963 | Memphis 0, 2Ole Miss 0 | Box score |
| Sep 21, 1963 | 9Navy 51, West Virginia 7 | Box score |
| Sep 21, 1963 | North Carolina 11, Virginia 7 | Box score |
| Sep 21, 1963 | NC State 36, Maryland 14upset | Box score |
| Sep 21, 1963 | 6Northwestern 23, Missouri 12 | Box score |
| Sep 21, 1963 | 4Oklahoma 31, Clemson 14 | Box score |
| Sep 21, 1963 | Oregon State 29, Utah 14 | Box score |
| Sep 21, 1963 | Penn State 17, Oregon 7 | Box score |
| Sep 21, 1963 | 1USC 14, Colorado 0 | Box score |
| Sep 21, 1963 | Stanford 29, San José State 13 | Box score |
| Sep 21, 1963 | Syracuse 32, Boston College 21 | Box score |
| Sep 21, 1963 | Tennessee 34, Richmond 6 | Box score |
| Sep 21, 1963 | TCU 10, Kansas 6 | Box score |
| Sep 21, 1963 | Texas Tech 16, Washington State 7 | Box score |
| Sep 21, 1963 | UTEP 34, North Texas 7 | Box score |
| Sep 21, 1963 | Utah State 43, Arizona 0 | Box score |
| Sep 21, 1963 | VMI 14, George Washington 6 | Box score |
| Sep 21, 1963 | Wichita State 33, Arizona State 13upset | Box score |
| Sep 21, 1963 | William & Mary 7, The Citadel 0 | Box score |
| Sep 21, 1963 | 7Wisconsin 41, Western Michigan 0 | Box score |
| Sep 21, 1963 | Xavier 21, Miami (OH) 12upset | Box score |
Everyone else
| Sep 21, 1963 | Catawba 18, Davidson 14 | Box score |
| Sep 21, 1963 | Furman 14, Vanderbilt 13upset | Box score |
| Sep 21, 1963 | Idaho 32, Fresno State 8 | Box score |
| Sep 21, 1963 | Mississippi State 43, Samford 0 | Box score |
| Sep 21, 1963 | Morehead State 19, Marshall 6upset | Box score |
| Sep 21, 1963 | Nebraska 58, South Dakota State 7 | Box score |
| Sep 21, 1963 | Tulsa 23, Montana State 13 | Box score |
| Sep 21, 1963 | Villanova 21, West Chester 9 | Box score |
| Sep 21, 1963 | West Texas 22, Texas–Arlington 17 | Box score |
| Sep 21, 1963 | Wyoming 35, Montana 0 | Box score |