1906: Week 1
Eight games. Winners are listed first; numbers before names are AP ranks going in.
FBS vs. FBS
| Sep 22, 1906 | Carlisle 6, Villanova 0 | Box score |
| Sep 22, 1906 | Harvard 7, Williams 0 | Box score |
Everyone else
| Sep 22, 1906 | Dartmouth 5, Norwich 0 | Box score |
| Sep 22, 1906 | Holy Cross 6, Massachusetts 4 | Box score |
| Sep 22, 1906 | Kansas 18, William Jewell 0 | Box score |
| Sep 22, 1906 | Lehigh 21, Albright 0 | Box score |
| Sep 22, 1906 | Penn State 24, Lebanon Valley 0 | Box score |
| Sep 22, 1906 | Swarthmore 65, USS Washington 0 | Box score |